Description

Overview

The primary aim of this course is to provide foundational statistics knowledge for genetic counseling students who are preparing for the genetic counseling certification exam. It is also suitable for practicing GCs who wish to have a refresher course on genetic counseling-related statistics. 

The Statistics Educational Program in Genetic Counseling consists of 25 lessons with video-lectures and statistics problem sets designed to be completed within approximately 5 weeks (1 lesson per statistics topic per day) or at your own pace.

Topics include:

• Pedigree Analysis
• Rules of Probability
• Hardy Weinberg Equilibrium
• Consanguinity, Degree of Relationship, Coefficient of Relationship, Coefficient of Inbreeding
• Autosomal Recessive, Autosomal Dominant, and X-Linked Recessive Probabilities
• Autosomal Recessive, Autosomal Dominant, And X-Linked Recessive Bayesian Analysis
• Haldane’s Rule
• Sensitivity, Specificity, Positive and Negative Predictive Values

This course is planned and hosted by the University of Minnesota Genetic Counseling Program, Department of Genetics, Cell Biology, and Development. For questions about course content, please contact gcgrad@umn.edu.

The content in this short course was authored by a genetic counseling master’s student as part of a master’s thesis project and was reviewed by University of Minnesota Genetic Counseling Program faculty. Curated resource lists, video-lectures, and self-paced assessments with tailored quiz feedback round out this unique, accessible educational course.

Target Audience

The primary audience for this course includes genetic counseling students studying for the certification examination and practicing GCs who wish to refresh their understanding of statistical concepts.

Registration

• Registration Rates: $49, payable by credit card only.
• Registrations for groups of 6 or more are eligible for a $10 discount per person.  Please contact cbs-rlt@umn.edu for further instructions before registering.
• For organizations wanting to purchase multiple seats in the course, also contact cbs-rlt@umn.edu for further instructions before registering.

For questions concerning registration, contact the CBS Research and Learning Technologies department at cbs-rlt@umn.edu.

Cancellation Policy

All registrations are final.  No refunds.

Objectives

At the conclusion of this course, learners should be able to:

• Analyze a pedigree with autosomal dominant inheritance.
• Calculate risks for a given autosomal recessive, autosomal dominant, or X-linked recessive condition for individuals, their children, and other relatives.
• Combine risks to determine chance of carrier parents having an affected child.
• Assess how consanguinity increases risks for autosomal recessive conditions.
• Apply the Hardy Weinberg Equilibrium to determine population carrier frequency or a condition’s incidence from a given carrier frequency.
• Understand what the coefficient of relationship (R) and the coefficient of inbreeding (F) mean conceptually and in practice.
• Use Bayesian analysis to evaluate an individual's risk for an autosomal dominant or autosomal recessive syndrome given specific modifying family history information, features, and/or genetic testing information.
• Use Bayesian analysis to evaluate an individual's risk for an X-linked syndrome given specific modifying information.
• Use Bayesian analysis to evaluate an individual's risk for an autosomal recessive syndrome given modifying information regarding carrier screening.
• Use Bayesian analysis to evaluate a couple’s risk to have a child with an autosomal recessive syndrome given their carrier detection information.
• Calculate sensitivity and specificity for a screening test.
• Calculate the positive predictive value (PPV) and the negative predictive value (NPV) for a screening test.

Accreditation

Genetic counselors who participate in this professional development activity may submit their Statement of Participation to their appropriate accrediting organizations or state boards for consideration of credit. The participant is responsible for determining whether this activity meets the requirements for acceptable continuing education.

Please direct any inquiries regarding credit and/or Statements of Participation to the University of Minnesota Genetic Counseling Program, Department of Genetics, Cell Biology, and Development, at gcgrad@umn.edu.